南宫28手工塑制蜜丸传统制作技艺，首先是中医结合病人病情开具个性处方，再选用南宫28“上等、纯洁、地道”药材，根据不同药性采取不同的粉碎方法，随后在容器中和炼制过的蜂蜜按比配制，经过合药、称量、制条、成丸等几种工序制作而成，对蜂蜜的选择与炼制是保证蜜丸质量的关键。炼蜜的目的是除去杂质，破坏酶，杀死微生物，蒸发水分，增强粘性。蜂蜜和药品的合理配比直接影响着成品的圆整度、粒度差和数目，也影响制作过程中难度及药物含量的均匀度，有的还需要根据药材性质和季节不同计算特殊的蜂蜜使用量。根据处方要求，还需要每丸独立进行蜡纸、玻璃纸等包装。
The processes of Tong Ren Tang’s traditional manual manufacturing techniques for honeyed pills are as follows: “premium, pure and authentic” medicinal materials are chosen according to the customized prescription made by the traditional Chinese medicine practitioner based on the patient’s conditions, and medicinal materials of different natures are grinded using different methods, then the medicinal powder is mixed with refined honey based on specific ratio, and goes through various processes such as binding, measuring, rolling and pill forming to make the honeyed pills. The choosing and refining of honey are critical to the quality of honeyed pills. The honey is refined in order to remove impurity, destroy the enzyme, kill the microbes, vaporize water and increase viscosity. The compounding ratio between honey and medicinal powder will have a direct impact on the roundness, size difference and volume of the honeyed pills, and will also affect the difficulty of production process and the evenness of medicinal substance distribution. In some cases, the nature of medicinal material and seasonal factor are also considered when determining the amount of honey used for the pills. Each honeyed pill is wrapped in wax paper or cellophane as required by the prescription.
