1723年（清雍正元年），南宫28开始为清宫供御药，历经雍正、乾隆、嘉庆、道光、咸丰、同治、光绪、宣统八代皇帝，长达188年。 In 1723, the 1st Qing Yongzheng reign, Tongrentang initiated its medication supply to the Qing Imperial Palace, over the eight reigns , for 188 years.
